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Revaree review, what hyaluronic acid inserts do for vaginal dryness

Revaree is Bonafide's hormone free hyaluronic acid insert for vaginal dryness. What is in it, what the published research on vaginal hyaluronic acid shows, how the original compares with Revaree Plus, and when Replens, YES VM or a silicone insert is the better buy.

By the Wet Betty editors ยท Published Oct 17, 2026

Fact checked against FDA 510(k) filings, WHO guidance and the sources listed below. How we review

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Revaree is Bonafide's hormone free vaginal insert with 5 mg of hyaluronic acid, used every two to three nights to relieve dryness. Research on vaginal hyaluronic acid is reasonably positive, though low dose vaginal estrogen usually does somewhat better head to head. It suits mild to moderate dryness, and Bonafide says it is not compatible with condoms.

The verdict.

Revaree is a sensible first insert for mild to moderate dryness if you prefer a no mess melt over a gel; give it a month of use every two to three nights, and remember Bonafide says it is not compatible with condoms.

The short version.

Revaree does one job: it puts a small dose of hyaluronic acid against the vaginal lining a few times a week so the tissue holds more water. It is a moisturizer, used on a schedule, not a lube for sex. The evidence for the ingredient is better than for most products in the dryness aisle. The trade offs are cost per month, some leakage as the insert melts, and the condom warning. If those do not bother you, it is an easy routine to keep.

What is in Revaree.

Each Revaree insert contains 5 mg of hyaluronic acid. Bonafide lists the rest as semi synthetic glycerides and the sodium salt of hyaluronic acid, a waxy base that melts at body temperature. There are no hormones, no fragrance and no applicator. Revaree Plus doubles the dose to 10 mg per insert and is sold for dryness that comes with pain or very sensitive tissue.

Hyaluronic acid is a sugar molecule the body already makes. It binds a lot of water, which is why it shows up in skin serums and eye drops. In the vagina the idea is the same: draw and hold moisture in tissue that has thinned and dried, most often from the drop in estrogen around menopause, after childbirth, while breastfeeding or during some cancer treatments.

Bonafide says Revaree is cleared by the FDA as a Class II medical device. That is a different route from a dietary supplement; the device clearance covers the product's safety and its stated use as a moisturizer.

How to use it.

Bonafide's directions are one insert every 2 to 3 nights. It suggests bedtime, inserting it while lying down and staying lying down for about 30 minutes so it can melt and spread. Expect some leakage as the base melts, which is another reason bedtime works. Bonafide reports earliest relief at around nine days and its headline results at 30 days, so a fair trial is about a month of steady use.

Two cautions from the brand. Revaree is not compatible with condoms, and it is not a contraceptive or a spermicide. If you use condoms, plan your nights or choose a different moisturizer. For sex itself you still want a lube; our vaginal moisturizer vs lube guide explains why both often have a place, and best silicone lube covers the long lasting options.

What the evidence shows.

The research is about vaginal hyaluronic acid in general, in gels, tablets and inserts from several makers, not about the Revaree brand alone.

Systematic reviews. A 2021 review in Climacteric pulled together 17 studies of hyaluronic acid used on the vulva or in the vagina. Hyaluronic acid generally improved painful sex, itching, burning and dryness, along with signs such as bleeding and vaginal pH. The authors still called for a well designed randomized trial to settle how well it works. A 2026 meta-analysis of 11 randomized trials found that three placebo controlled trials showed improvements in vaginal health scores, dryness related quality of life and sexual function, and that hyaluronic acid was not inferior to the active comparators. It rated the evidence moderate for dryness and sexual function and low for some other outcomes.

Against estrogen. In a small randomized trial of 42 postmenopausal women, 5 mg hyaluronic acid vaginal tablets, the same dose as Revaree, and estradiol vaginal tablets both relieved symptoms over 8 weeks. Both lowered vaginal pH and improved the tissue. The estradiol group improved more. A 2023 systematic review of six head to head studies reached a similar view: both work, and estrogen was better in most direct comparisons.

Bonafide's own numbers. On its product page, Bonafide cites four head to head trials against vaginal estrogen creams and reports that 91 percent of women saw symptom improvement by day 30, with an 86 percent reduction in itching and burning. Those are the brand's figures from its summary of the research, and we have not seen them pooled in an independent review.

Where it fits. The Menopause Society's 2020 statement on genitourinary syndrome of menopause says nonhormone products sold without a prescription give enough relief for most women with mild symptoms, while vaginal estrogen, vaginal DHEA and ospemifene are effective for moderate to severe symptoms. Revaree belongs in that first group. If a month of it barely helps, ask a clinician about the prescription options; vaginal atrophy explains what they are.

Revaree compared with Replens, YES VM and Liquibeads.

Product Active approach Format Use Condoms
Revaree 5 mg hyaluronic acid Melting insert Every 2 to 3 nights Not compatible, per Bonafide
Revaree Plus 10 mg hyaluronic acid Melting insert Every 2 to 3 nights Not compatible, per Bonafide
Replens Polycarbophil gel Prefilled applicator About every 3 days Latex and polyisoprene, not polyurethane, per the maker
YES VM Water based plant gel Applicator gel As needed Water based; check the label
K-Y Liquibeads Silicone based Bead insert Per the label Latex compatible, per the listing

Replens. Replens is the moisturizer clinicians name most often, a polycarbophil gel that clings to the lining and is usually used every three days. Its FDA filing lists a pH of 2.5 to 3.5 and an osmolality of 1,200 to 2,011 mOsm/kg, high enough that some people with fragile tissue feel a sting. It has the longer research record and condom guidance from its maker. Our Replens review goes deeper.

YES VM. YES VM has the best published numbers of any moisturizer on our index, 250 mOsm/kg and a pH of 4.15, close to the body's own. It is organic and glycerin free and can double as a lube. If Replens stings, start here. Our lube osmolality explainer covers why those numbers matter.

K-Y Liquibeads. Liquibeads are silicone based beads that melt into a coating. They are another no applicator mess format for people who like the idea of an insert but want something other than hyaluronic acid.

Revaree Hyaluronic Acid Inserts
Our Revaree pickNo. 1

Revaree Hyaluronic Acid Inserts

Moisturizer from Bonafide. Hyaluronic acid inserts, 5 mg.

Our take. Hormone free hyaluronic acid insert used every two to three days. Pricey, but the format people stick with.

Pros

  • Hormone free hyaluronic acid
  • Insert format people stick with
  • Lasts two to three days

Cons

  • Expensive per dose
  • No published osmolality
OsmolalityWHO bandpHGlycerin freeLatex condom safeSilicone toy safe
Not publishedNot applicablen/aYesNoYes
Bonafide Revaree Plus Hyaluronic Acid Inserts
Stronger doseNo. 2

Bonafide Revaree Plus Hyaluronic Acid Inserts

Moisturizer from Bonafide. 1 month supply, 10 mg hyaluronic acid inserts.

Our take. The double strength Revaree, 10 mg of hyaluronic acid per insert, for dryness with pain or very sensitive tissue.

Pros

  • 10 mg hyaluronic acid per insert, twice the original
  • Hormone free
  • Used every two to three nights, not daily

Cons

  • Bonafide says Revaree is not compatible with condoms
  • No published osmolality or pH
OsmolalityWHO bandpHGlycerin freeLatex condom safeSilicone toy safe
Not publishedNot applicablen/aYesNoYes
Replens Long-Lasting Vaginal Moisturizer
Most studied gelNo. 3

Replens Long-Lasting Vaginal Moisturizer

Moisturizer from Replens. 8 applicators.

Our take. The best known moisturizer, and the one gynecologists name first. Low pH, high osmolality, used every three days rather than during sex.

Pros

  • The moisturizer gynecologists name first
  • Low pH, 2.5 to 3.5
  • Lasts about three days per dose

Cons

  • High osmolality, 1,200 to 2,011 mOsm/kg
  • Contains glycerin
  • Used on a schedule, not during sex
OsmolalityWHO bandpHGlycerin freeLatex condom safeSilicone toy safe
1,200 to 2,011 mOsm/kgHigh2.5 to 3.5NoYesYes
YES VM Vaginal Moisturizer
Best numbersNo. 4

YES VM Vaginal Moisturizer

Moisturizer from YES. 3.5 oz.

Our take. The moisturizer with the best numbers on our ledger: iso-osmolar and pH matched. Organic, UK made.

Pros

  • Best numbers of any moisturizer, 250 mOsm/kg and pH 4.15
  • Organic, glycerin free
  • Can double as a lube

Cons

  • Pricier than drugstore moisturizers
  • Harder to find in stores
OsmolalityWHO bandpHGlycerin freeLatex condom safeSilicone toy safe
250 mOsm/kgIdeal4.15YesYesYes
K-Y Liquibeads Vaginal Moisturizer
Silicone insert alternativeNo. 5

K-Y Liquibeads Vaginal Moisturizer

Moisturizer from K-Y. 6 ovules with applicators.

Our take. Silicone ovules that melt into a slick, long lasting layer. A moisturizer that also works as a lube.

Pros

  • Silicone based, very long lasting
  • Doubles as a lube
  • Latex condom compatible per the label

Cons

  • Silicone, so not for silicone toys
  • Capsule contains glycerin
OsmolalityWHO bandpHGlycerin freeLatex condom safeSilicone toy safe
Not publishedNot applicablen/aNoYesNo

Wet Betty may earn a commission when you buy through links on this page. As an Amazon Associate we earn from qualifying purchases. It never changes what we recommend. Why trust us?

Bonafide Revaree, our Revaree pick.

Revaree is the right starting dose for mild to moderate dryness. The insert format means no applicator to wash and no gel on your fingers. It has no published osmolality or pH, which is normal for a melting insert but means we cannot place it on our index.

Bonafide Revaree Plus, stronger dose.

Revaree Plus has 10 mg of hyaluronic acid per insert. It makes sense if the original helped but not enough, or if dryness comes with pain. There is no published trial comparing the two doses, so the step up is a judgment call.

Replens, most studied gel.

Replens is the gel to try if you want condom compatibility and the longest track record, and you do not mind applicators.

YES VM, best numbers.

YES VM is the gentlest choice by the numbers and the one we would pick for sensitive tissue.

K-Y Liquibeads, silicone insert alternative.

K-Y Liquibeads give a slick silicone coating from a small insert. Silicone products are not for use with silicone toys.

Who Revaree suits.

  • A good fit. You have mild to moderate dryness, you want to avoid hormones or cannot use them, you dislike gels and applicators, and condoms are not part of your routine.
  • Think twice. You rely on condoms, your tissue is very sensitive, or you need relief during sex more than between sex. A condom friendly gel and a separate lube may serve you better; see best vaginal moisturizers and lube for menopause dryness.
  • Not enough on its own. Dryness is severe, sex is painful despite moisturizer and lube, or you have urinary symptoms too. That is the point to ask about prescription treatment. Our how to treat vaginal dryness guide walks through the steps in order.

When to see a clinician.

See a clinician if dryness has not improved after a month or two of regular moisturizer use, if sex is painful, if you have bleeding after menopause or after sex, or if you notice discharge with a strong smell, itching or sores, which point to an infection rather than dryness. If you have had breast or another hormone sensitive cancer, ask your oncology team before starting any vaginal product. Ask about vaginal estrogen, vaginal DHEA or ospemifene if over the counter products are not enough. This page is general information, not medical advice.

Frequently asked questions.

Does Revaree really work?

The ingredient has reasonable evidence. Reviews of vaginal hyaluronic acid trials find it improves dryness, itching, burning and painful sex, and a 2026 meta-analysis rated that evidence moderate. Head to head, low dose vaginal estrogen usually did somewhat better. Revaree itself is a 5 mg hyaluronic acid insert, the same dose tested in one of those trials.

What is the difference between Revaree and Revaree Plus?

Dose. Revaree has 5 mg of hyaluronic acid per insert and Revaree Plus has 10 mg. Bonafide positions Plus for dryness with pain or sensitive tissue. Both are used every 2 to 3 nights.

How long does Revaree take to work?

Bonafide says some women notice relief in about nine days and reports its main results at 30 days. Give it a month of regular use every two to three nights before you judge it.

Can you use condoms with Revaree?

Bonafide says Revaree is not compatible with condoms. If you rely on condoms, choose Replens, which its maker says works with latex and polyisoprene condoms, or a water based gel such as YES VM, and check both labels.

Is Revaree safe after breast cancer?

Revaree is hormone free, which is why nonhormonal moisturizers are often the first suggestion for survivors. Ask your oncology team before starting any vaginal product, and mention any treatment you are on.

Revaree or Replens, which is better?

Both are hormone free moisturizers used every few days. Replens is a polycarbophil gel with the longer research record and a known high osmolality. Revaree is a melting hyaluronic acid insert with no applicator mess, but it is not condom compatible. If one stings or leaks too much for you, try the other.

Sources

  1. 1.Revaree hormone free vaginal moisturizer, Bonafide.
  2. 2.Hyaluronic acid in vulvar and vaginal administration, evidence from a literature systematic review, Buzzaccarini G et al. Climacteric, 2021.
  3. 3.The comparison of hyaluronic acid vaginal tablets with estradiol vaginal tablets in the treatment of atrophic vaginitis, a randomized controlled trial, Ekin M et al. Archives of Gynecology and Obstetrics.
  4. 4.Hyaluronic acid for vaginal health and quality of life in postmenopausal women, a systematic review and meta-analysis of randomized controlled trials, International Journal of Gynecology and Obstetrics, 2026.
  5. 5.The 2020 genitourinary syndrome of menopause position statement of The North American Menopause Society, The Menopause Society. Menopause, 2020.